Kendall's tau measuring CSC-specific expression versus all other cell types in the selected dataset. CSC clusters defined by PROM1/CD44/ALDH1A1 co-expression.

Confidence that the protein is surface-localised, based on ≥2 of: TMHMM transmembrane helices, SignalP signal peptide / GPI anchor, UniProt GO:surface, CSPA experimental confirmation.

Pharos IDG tier reflecting absence of drug development activity and limited biological characterisation. Tdark = <5 PubMed papers, no approved drugs, no MoA. Tbio = some biology known, still no drugs.

On-target normal tissue toxicity risk based on expression in heart, liver, kidney, and neurons. Safety flag is raised when expression exceeds the 20th percentile of safe reference targets.